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Doubtless a good chunk of that financing will go towards trying to wrangle with regulatory variations in its different markets.
In maize, a review showed the potential contributions of allelic variation to heterosis (Springer and Stupar, 2007b) and the prevalence of cis-acting regulatory variations which contribute to biased allelic expression (Springer and Stupar, 2007a).
The latter three transcripts are not located on previously identified chromosome segments introgressed from the donor BALB/cJ strain, supporting the suggestion of trans-acting regulatory variations among strains.
Understanding the complexity of these regulatory variations is essential.
We deciphered here the source of these regulatory variations of the THI and PDC genes.
Given the small size of the population, these data did not intend to decipher the regulatory variations globally.
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Regulatory variation influencing gene expression is a key contributor to phenotypic diversity, both within and between species.
While the chromatin accessibility landscape of this process has been explored in defined populations, single-cell regulatory variation has been hidden by ensemble averaging.
Genes involved in immunity tend to permit regulatory variation [8], as do multicopy genes [52].
The estimated value of δ does not imply that 24% of genes are without cis-acting regulatory variation.
Hence, identification and characterization of ASGE will help us to appreciate the extent of functionally important regulatory variation.
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