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A successful network had to be able to take two clearly different regulatory trajectories, equivalent to lytic and lysogenic development.
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There are many stakeholders influencing the regulatory trajectory of quantitative structure-activity relationships (QSAR) models, including regulators, industry, model developers and consultants.
Industry groups have continued to influence the regulatory trajectory of policies surrounding the use of antimicrobials in food animal production.
However, while this regulatory to policy trajectory was emerging, LCA was taking hold of the academic interest.
Taken together, these data are in accordance with and strengthen the known concept of Smad- and non-Smad-dependent TGF-β pathways and provide for the first time trajectories for regulatory ligands.
Each individual component g k : Π → { 0, 1 } is called the k th regulatory function, and a trajectory of the system is a function s : N → Π such that s ( t + 1 ) = g ( s ( t ) ) for every t ∈ N. Since the state space is finite, each trajectory must eventually become periodic.
To this aim, reaction-diffusion models based on ODEs were implemented, which have been employed succesfully to reproduce early patterning processes and infer possible regulatory changes underlying mutant expression trajectories in the Drosophila embryo [29] [32].
Increasing evidence suggests that prenatal exposure to a hyperglycemic environment can alter growth trajectories and homeostatic regulatory mechanisms, thus causing lifelong changes that result in an increased risk of overweight and obesity (2– 5).
Speciffically, I explored the way in which succesively accumulating mutations in a virtual embryo carrying a reference regulatory network impinged on the expression trajectories.
Changes in the architecture of gene regulatory networks likely influence the evolutionary trajectory of social traits.
We suggest such R-genes follow a different evolutionary trajectory than genes with regulatory roles [ 38].
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