Sentence examples for regulatory tolerance from inspiring English sources

Analyses of T-cell function both regulatory (tolerance) and effector (β-cell killing)—are highly demanding and poorly reproducible between most laboratories.

Oral administration of LGG resulted in elevated IL-10 concentrations in atopic children, indicating that specific probiotics may have anti-inflammatory effects in vivo and may possibly enhance regulatory or tolerance-inducing mechanisms as well.

Experimental models of transplantation provide strong support for the role of regulatory cells in tolerance.

On the other hand, at the limit of infinite cooperativity, i.e. Boolean regulatory interactions, the tolerance reaches 89%.

More recently, the KP has been found to be an important determinant of immune responses and regulatory T-cell tolerance.

Myeloid dendritic cells (mDC) have a central regulatory role in tolerance and immunity.

Since PP2B is a crucial signaling molecule in regulating adaptive immunity [52] a potential inhibitory effect of axotrophin on PP2B activity may present an immune tolerance regulatory mechanism in addition to LIF receptor downregulation.

OX40L has been shown in vitro to inhibit the generation of IL-10-producing T regulatory cells needed for tolerance, and it is known that mutations in this pathway cause loss of tolerance and autoimmunity [ 93].

Treatment with a cocktail of CD4 and CD8-specific monoclonal antibodies (mAb) induces long-term transplantation tolerance and regulatory CD4+ T cells that induce tolerance in non-tolerant T cells.

To explore regulatory mechanisms of butanol tolerance, in this work, by constructing gene knockout mutants of the butanol-responsive TCSTS genes and conducting tolerance analysis, we uncovered that an orphan slr1037 gene encoding a novel response regulator was involved in butanol tolerance in Synechocystis.

There is no tolerance, either regulatory or in public perception, for a human gene-based pharmaceutical to end up in the world's food supply".