Sentence examples for regulatory themes from inspiring English sources
Mechanisms of crosstalk, by which non-enzymatic proteins integrate metabolic cues with the action of interfacial enzymes, represent unappreciated regulatory themes in lipid signaling.
Regulatory themes within exCs were visualised using hierarchical clustering of robust, annotated motifs using binary distance and average linkage.
We visualised regulatory themes within exCs using hierarchical clustering of the presence of significantly scoring binding site motifs, further indicating the presence of exCs-specific patterns (Figure 3).
In sum, the GO analysis pointed to several regulatory themes that seem to be important specializations of HVC, as discussed in more detail in the following sections.
The user may also employ TF-target associations to identify common regulatory themes that may be associated with a set of co-expressed functionally similar genes.
Five dominant legal and regulatory themes were identified through analysis: (1) liability; (2) immigration law; (3) physician licensing; (4) corporate ownership; and (5) reputational protection.
C1 Copps Pushes for Regulation Michael J. Copps, the lone Democrat at the Federal Communications Commission, has sounded a broad regulatory theme at a time when his colleagues are pressing for deregulation.
Although the ACT domains have high sequence divergence, there is a common regulatory theme among these domains.
We imagine that the integration between Hh and Ret via Gas1 is extended to other contexts as a general regulatory theme.
A regulatory theme has emerged at many imprinted clusters in which a single long non-coding RNA (lncRNA) is thought to repressively regulate genes in cis through direct transcriptional blocking and/or recruitment of repressive chromatin remodeling complexes such as G9a and PRC2, resulting in differential allele-specific histone modifications [ 3, 4].
Indeed, the common regulatory theme of lncRNA-mediated control of HOX genes is recruitment of chromatin modifying complexes catalyzing these modifications, such as cis-activation of HOXA cluster by HOTTIP lncRNA-mediated recruitment of WDR5/MLL complex causing H3K4me3 modification [ 32], or trans-repression of HOXD genes by HOTAIR lncRNA recruiting PRC2 complex that imposes H3K27me3 mark [ 33].
