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The regulatory strength method is shown here to be topology-dependent.
We tested whether the repeated practice of self-control could improve regulatory strength over time.
Three methods for establishing and quantifying causal relationships between genes based on steady-state measurements in single-gene perturbation experiments have recently been proposed: the regulatory strength method, the local regulatory strength method, and Gardner's method.
Participants entered a four-month self-control exercise drill designed to increase regulatory strength: a financial monitoring program.
The toggle switch is controllable in the sense that the gap between the bistable states is adjustable as determined by the regulatory strength from the driver nodes.
Consequently, CEBPE-to-RETN regulatory strength can change considerably upon various conditions and in certain cell type (Table 2).
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The regulatory strengths obtained by this method can also be used to compute local regulatory strengths.
The Danish firm Lunar Way decided to take this up a notch by partnering with local banks for regulatory strengths, so as to focus on technology and user experiences.
The results generated by Gardner's method and by the two regulatory strengths methods differ only by scaling constants, but Gardner's method requires more measurements.
The introduced metrics quantify those underlying regulatory strengths, directions between pair candidates globally and comparatively.
The supervised learning framework mainly covers two aspects, namely, it should characterize pairwise regulatory strengths and constrain subsequent computational redundancy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com