Sentence examples for regulatory prediction from inspiring English sources
The effect of model parameter uncertainty is accounted for through first-order sensitivity analysis for the ensemble/validation tests, and first-order sensitivity analysis and Monte-Carlo analysis for the regulatory prediction.
From this paper the "Regulatory Potential Score" appeared to be the most promising and accessible regulatory prediction dataset we could compare to our data.
Most bioinformatics protocols for regulatory prediction consist in the application of two steps (reviewed in [ 14- 16]): (i) sequence analysis in search of consensus sites derived from catalogs of predictive models or motif discovery approaches; and (ii) evaluation of such predictions, taking into account evolutionary conservation across other species.
It is likely that current predictors will include chromatin and epigenomics information in the near future to refine their predictive output; however, to our knowledge, the CBS platform of regulatory predictions is the first tool that integrates information on computationally identified TFBSs and histone modification marks to characterize Drosophila genomes.
The key regulatory predictions have been verified by an experiment and literature survey.
We then used the model to identify the best regulatory predictions across the three data sets.
Application of the SPF method to a gWormNet led to promising regulatory predictions for eQTL-hotspots.
Thus, the consistency of gene regulatory predictions can be evaluated and tested using the novel CoryneCenter functionality.
As shown in the following application case, the user can test or (in validate hypotheses that microarray experiments or automated regulatory predictions have generated.
It is also interesting that clusters 4, 6, and 8 are highly anti-correlated in their regulatory predictions in mouse, reflecting significant differences between species.
Experimental confirmation of regulatory predictions by NolR was also found for nodA, nodD1, nodD2 and nodM [ 42], by Fur for sitA [ 43], by NesR for the metHK operon and the ahcY gene [ 44] and by ChvI for ropB [ 45].
