Sentence examples for regulatory potentials from inspiring English sources

Our approach is different in that we integrate multiple data sources at the genome level, which is indeed necessary for incorporating nucleosome information, regulatory potentials, etc.

Therefore, we first evaluated the distribution of multispecies conservation scores (PhastCons score) [41] and regulatory potentials (RegPotential score) [42] for positions in the functional and non-functional STAT3 TFBSs detected by STAT-Scanner using the reference set of 22 genes (Table S1).

For each gene g, rank the candidate regulators based on the regulatory potentials predicted from the supervised framework.

TM2H cells (p53 null), in contrast, lack both negative regulatory potentials of acetylated p53 and the availability of nuclear p21.

The prior probability and, therefore, the prior odds, of a candidate model are formulated as a function of regulatory potentials.

For each TF we defined the gene sets M100, M200, M500 and M800 as the 100, 200, 500, or 800 genes with the highest regulatory potentials.

The additional data sources used here are conservation, regulatory potential, DNA duplex stability, and nucleosome positioning.

In addition to these innate immune functions, human GM-CSF-activated monocytes simultaneously have a regulatory potential on adaptive immunity.

Furthermore, we evaluated the regulatory potential of a large genomic interval by deleting a 1.5 Mb fragment.

Within the vast landscape of histone modifications lysine methylation has gained increasing attention because of its profound regulatory potential.

Table 1 also demonstrates that the AUC scores for combining DNA energy with conservation or regulatory potential are higher than those obtained with single additional information sources.