The additional data sources used here are conservation, regulatory potential, DNA duplex stability, and nucleosome positioning.
In addition to these innate immune functions, human GM-CSF-activated monocytes simultaneously have a regulatory potential on adaptive immunity.
Furthermore, we evaluated the regulatory potential of a large genomic interval by deleting a 1.5 Mb fragment.
Within the vast landscape of histone modifications lysine methylation has gained increasing attention because of its profound regulatory potential.
Comparing the regulatory regions of the SLC6A3 and the SLC6A4 revealed their markedly different regulatory potential.
Thus, our analysis has greatly expanded the regulatory potential of microtubule organization in budding yeast.
We analyzed each of the sites for their regulatory potential (RP) scores (Figure 3B).
These core sequences are necessary but not sufficient for full regulatory potential.
The last three rows show the probabilities of conservation, nucleosome occupancy and the regulatory potential.
Previous studies have used evolutionary conservation as an indicator of regulatory potential.
Regulatory potential scores (log-likelihoods) are obtained using ESPERR [73] that also makes use of multiple genome alignments.
