Sentence examples for regulatory pool from inspiring English sources

After a short lag, it also increases the ER's PFO-accessible regulatory pool.

However, under modern human dietary conditions, the major determinant of a regulatory pool of LDL-apoB100 is hepatic LDL particle clearance.

When LDL-derived cholesterol leaves lysosomes, it expands PM's PFO-accessible pool and, after a short lag, it also increases the ER's PFO-accessible regulatory pool.

It is possible that maturing DCs exposed in vivo to VIP might differentiate into regulatory DCs that help to keep the regulatory pool 'topped up'.

Recycling of cholesterol without expansion of the regulatory pool would also explain why cholesterol synthesis continues in the livers of patients with homozygous FH.

Furthermore, the activity of the LDL pathway, and therefore the concentration of LDL in plasma, is governed by the concentration of cholesterol within a key intracellular regulatory pool.

The finding of unaffected cholesterol mass in the presence of increased Cav1 expression and decreased mSREBP are consistent with a model in which knockdown of CFTR in human AM induces a redistribution of regulatory pools of cholesterol.

Decreasing VLDL secretion will not necessarily increase total cholesterol mass within the hepatocyte as it may allow more time for equilibration with the regulatory pools and therefore decreased synthesis and uptake.

By contrast, cholesterol that enters the hepatocyte directly or within chylomicron remnant particles will enter the exchangeable and regulatory pools of cholesterol before it can be esterified and secreted from the cell.

In brief, we hypothesize that most of the cholesterol that enters the hepatocyte as part of an LDL particle is secreted from it as part of a VLDL (very low-density lipoprotein) particle without coming into full equilibrium with the exchangeable and regulatory pools of cholesterol within the hepatocyte.

If increased, the regulatory heme pool may repress ALAS1, and its depletion causes ALAS1 induction.