Sentence examples for regulatory modifications from inspiring English sources

Because the HoxD cluster remained entirely untouched by the insertional events, we investigated whether these phenotypes were induced by regulatory modifications at a distance.

They can be used for testing which genetic and regulatory modifications can increase the production of metabolites of interest, while simultaneously monitoring other key functions of the host organism.

Any proposed regulatory modifications resulting from the concept release would be subject to rulemaking procedures, including public comment, and any changes that imposed new regulatory obligations or restrictions would be applied prospectively only".

Although GSK3β is a constitutively active kinase, its activity is subject to modulation, and phosphorylation at its serine-9 residue is well recognized as one of the primary regulatory modifications [32] [36].

Interestingly, it possesses only one (N-terminal) of the two nuclear localization signals that are seen in other mammalian poly(A) polymerases, and lacks the C-terminal domain that is involved in various regulatory modifications and interactions.

Therefore, regulatory modifications to pricing are required.

ERK1/2 phosphorylation of cortactin has emerged as an important positive regulatory modification, enabling cortactin to bind and activate the Arp2/3 regulator neuronal Wiskott-Aldrich syndrome protein (N-WASp), promoting actin polymerization and enhancing tumor cell movement.

These discoveries establish the complete reversibility of poly(ADP-ribosyl)ation as a regulatory modification.

Methylation of cytosine at CpG dinucleotides is an important epigenetic regulatory modification in many eukaryotic genomes.

Likewise, intracellular lysine residues can be used as sites of regulatory modification, such as ubiquitination.

The methylation of cytosines at CpG dinucleotides is an important regulatory modification in the somatic cells of mammals and other vertebrates [ 1, 2].