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Our knock-down analysis of the gap gene network in M. abdita provides causal regulatory explanations of how this can be achieved at the gene network-level.
This gives deeper insight into the the relevance of different regulators or regulator combinations, and lets one check for alternative regulatory explanations.
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A number of duplicate genes (especially purF and purP) have been identified, but a biochemical or regulatory explanation for these duplications has not been established.
Just as development is a system property of the regulatory genome, causal explanation of evolutionary change in developmental process must be considered at a system level.
Existing research on business participation in voluntary environmental programs emphasizes a variety of explanations, including regulatory pressure and incentives, market pressure, self-regulation, and firm size.
If you want to know more about the wrongheaded jobs versus environmental protections argument check out the report, "Regulatory Uncertainty: A Phony Explanation for our Jobs Problem" by EPI's Larry Mishel.
The inverse expression pattern of miR-143/-145 and PAI-1 prompted us to consider a miRNA regulatory mechanism as an explanation for our observations.
But the compelling point is that regulatory RNAs provide an explanation as to why complexity doesn't scale with the number of protein-coding genes.
This topic is of great relevance in the context of clarifying the equivocal role of FOXP3 and its partners for explanation of regulatory T cell circuits.
These data provide an obvious rationale to search for long-distance regulatory sequences as an explanation for a proportion of GWAS SNP associations.
The model has been extensively used elsewhere [ 42, 43, 51] to simulate and provide some explanations concerning the regulatory mechanism that leads to precise pattern formation.
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