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Functionally, CYPs catalyze the oxidative metabolism of lipophilic compounds including both exogenous and endogenous organic compounds, such as sterols, fatty acids, hormones, phytochemicals, antibiotics, drugs, food additives and environmental contaminants etc [3], [4], involved in the development of regulatory, essential metabolism and broad defense against various pollutants.
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ARE was cis- acting regulatory element essential for the anaerobic induction.
Vascular endothelial growth factor (VEGF) and its receptors VEGFR-1, soluble (s) VEGFR-1 and VEGFR-2 represent a regulatory system, essential for both physiological and pathological angiogenesis.
Collectively, the data delineate an alternative splicing regulatory network essential for spermatogenesis, the splicing factor that controls it, and its biological importance in germ-Sertoli communication.
These establish a core gene regulatory network essential for maintaining self-renewal and pluripotency [46].
Smooth muscle S1 containing the regulatory and essential light chains was expressed in an insect cell line as described [39].
Crx is an Otx-like homeobox transcription factor critical for photoreceptor differentiation and for maintenance of the transcriptional regulatory networks essential for normal retinal development [30]and pineal function[31] [33].
The non-structural rep gene encodes four regulatory proteins essential for viral replication, whereas cap encodes three structural proteins (VP1 3) that assemble into a 60-mer capsid shell.
In particular, WTAP appears to serve as a regulatory subunit essential for m6A methyltransferase activity.
Transcriptional gene silencing is a gene regulatory mechanism essential to all organisms.
Nevertheless, the noncoding regions are not junk DNA but contain many regulatory elements essential for gene expression as well.
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