Sentence examples for regulatory endpoints from inspiring English sources
They are used as regulatory endpoints to quantify removal dynamics and to assess persistence in soil.
On the other hand, these rankings, even if the exact numbers should not be taken too seriously, show which packages offer the most support in the task of deriving parameters and regulatory endpoints from chemical degradation data.
The Adverse Outcome Pathways (AOPs) are designed to provide mechanistic understanding of complex biological systems and pathways of toxicity that result in adverse outcomes (AOs) relevant to regulatory endpoints.
The difficulty of isolating and measuring these more subtle effects makes them impractical as regulatory endpoints.
Such an approach to early drug development in RA might increase the chances of success in later phase studies designed to meet the regulatory endpoints that are required to achieve approval.
It is just a matter of time until MRD negativity will become a regulatory endpoint for drug approval.
The WoE approach means that all available information is assessed through expert judgement for its suitability and reliability, and relative weights are assigned (e.g. quality of the data, consistency of results and/or data, nature and severity of effects, relevance of the information for the given regulatory endpoint).
For the moment, radiographic measurements combined with pain and function remain the regulatory endpoint in DMOAD development.
Based on specific guidelines and clinical trial programs that were developed to be consistent with regulatory guidance, endpoints in oncology are thoroughly evaluated in terms of their patient-relevance.
The presentation, diagnosis, and current therapeutic strategies are briefly reviewed, followed by a detailed discussion of the regulatory strategy, recommended endpoints, and future directions.
Additionally, eQTL mapping can be used to reconstruct regulatory networks involving endpoint traits and expression traits, resulting in information useful for selection decisions [12].
