Sentence examples for regulatory drift from inspiring English sources

Exact(2)

Damage to DNA means that the regulation of genes gets less precise, and this regulatory drift disrupts the stem cells that repair each tissue.

Regulated expression of microRNAs upon differentiation satisfies the hypothesized role of microRNAs in canalization, or stabilization of nascent cell types in the face of stochastic regulatory drift.

Similar(58)

This type of neutral network evolution producing the same output based on different regulatory principles is called developmental system drift or phenogenetic drift (Weiss and Fullerton, 2000; True and Haag, 2001; Weiss, 2005; Haag, 2007; Pavlicev and Wagner, 2012).

Moreover, whether drifts in regulatory states occur depends also on the ratio of time scales, for example, of histone modification and cell replication.

Introducing restrictions based on economic consequences of pollen drift "politicizes the regulatory process and goes beyond your statutory authority," Representative Frank D. Lucas, Republican of Oklahoma, who is the new chairman of the House Agriculture Committee, wrote to Mr. Vilsack on Jan . 19 before holding a hearing on the proposals the next day.

One factor underlying this lack of uniformity in immune response may be the stochastic nature of genetic drift acting on regulatory regions or functional genes associated with immunity.

I wonder if an alternative interpretation could be at least as plausible: population bottleneck -> regulatory innovations+fixation of TE via drift?

But he's been quietly drifting right on regulatory issues in recent years.

This cryptic regulatory turnover is termed 'developmental system/systems drift' (DSD) (True and Haag, 2001).

Furthermore, we made use of the known ancestral history of S288C to identify a key recent departure from mutation-purifying selection-drift equilibrium in the regulatory program of laboratory yeast.

In the following, we consider these drifts of the cells regulatory states on long time scales as aging.

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