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Feathers, originally evolved as a heat regulatory device among the reptilian ancestors of today's birds, are a good example.
In virtually all jurisdictions the key regulatory device is the requirement that new construction or substantial rehabilitation of old structures not be undertaken until official permission (such as a building permit) has been obtained.
Here, we present a novel scaffolding architecture of an inducible regulatory device.
Such a technique may be useful in studying the biological mechanisms which underlie the synthetic regulatory device of this work and others.
Most peripheral artery disease (PAD) clinical device trials are supported by commercial manufacturers and designed for regulatory device approval, with extensive inclusion/exclusion criteria to support homogeneous patient populations.
Other public officials have employed litigation as a regulatory device with uneven success.
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The ability to build transcriptional regulatory devices depends on the availability of programmable, sequence-specific, and effective synthetic transcription factors (TFs).
RNA aptamers can be assembled into genetic regulatory devices that sense and respond to levels of specific cellular metabolites and thus serve an integral part of designing dynamic control into engineered metabolic pathways.
Because all modules of the AND gates are functional in bacteria other than Streptomyces, we anticipate that these regulatory devices can be used to control gene expression in other Actinobacteria.
They can also be used as regulatory devices for controlling constitutive, inducible, tissue-preferred gene expression [ 49].
For a general review of natural RNA-based regulatory devices, see ref (89); the engineering and current diversity of synthetic devices are reviewed in refs (90) and (91), respectively.
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