Sentence examples for regulatory core from inspiring English sources

Furthermore, simulated dynamics and experimental validation of a regulatory core of the underlying gene-regulatory network revealed a negative-feedback loop that limits initial inflammation via hypoxia-mediated upregulation of Il10.

Furthermore, Sox2 in association with the POU domain transcription factor Oct4 and homeobox transcription factor Nanog form a regulatory core, which maintains self-renewal of the pluripotent ICM in the embryo and ES cells [4], [15], [20] [21], and is unique to mammals [22].

Therefore, no additional regulatory core sets are extracted.

This SCC constitutes the regulatory core, and its regulatory impact extends up to 74 genes, so the states of these 74 genes depend on the state of the master regulatory core.

Two stable states were found for the regulatory core, one with all nodes "off" and one with all nodes "on".

However, potentially it is possible to scale the algorithm for increased size of the regulatory core, but the attractor computation of the network model forms the bottle neck.

Hence insect-infecting viruses, carrying a B-type DdDp, are likely to have accreted GRNs around regulatory cores emerging from B-type cellular hosts [25].

This size range is chosen in accordance with regulatory cores of the selected biological examples.

The regulatory effect by the core set is propagated through stoichiometry throughout the model, recapitulating the experimentally observed changes.

Moreover, the spacing and orientation between the IL-2 regulatory and core promoter regions is important for setting the level of transcription.

The resources provided by the Irving Institute offer support in biomedical informatics, study design and biostatistics, bioethics, regulatory issues, core laboratory facilities, community engagement, plus a fully-staffed Clinical Research Resource for campus investigators.