Sentence examples for regulatory checkpoint from inspiring English sources

Phosphorylation and dephosphorylation of the C-terminal domain (CTD) of RNA polymerase II (Pol II) represent a critical regulatory checkpoint for transcription.

This is a regulatory checkpoint in normal cell homeostasis.

CTLA-4 is the archetypal immune regulatory checkpoint.

Oligonol acts as a regulatory checkpoint in lipid synthesis by increasing phosphorylation.

CTLA-4 was the first negative regulatory checkpoint receptor to be clinically targeted.

Cdk8 module RNAPII antagonism for Mediator binding represents a key regulatory checkpoint.

A second level of regulation allows adjustment of the expression of the particular catabolic operons in response to the global environmental conditions of the cells, and recent findings provide some clues about the mechanisms underlying such complex regulatory checkpoints.

Current data suggest that focusing development on agents countering immune suppression in the tumor microenvironment or blocking regulatory checkpoints to T-cell activation may have the greatest clinical yield.

Since emerging evidence indicates that TAG synthesis in microalgae operates through coordinated crosstalk between multiple pathways in diverse subcellular destinations including the endoplasmic reticulum and plastids, we discuss new experimental studies and models that incorporate these findings for discovering key regulatory checkpoints.

Eight Lotus mutants arrested at different stages in the symbiotic process and a root nodule developmental time-series was profiled in order to define important regulatory checkpoints.

Based on our working model of cellular states, promoter-luciferase transcriptional fusions were generated for genes at regulatory checkpoints in several key metabolic pathways (Figure 3).