Sentence examples for regulatory alterations from inspiring English sources
Through proteomics approaches, the understanding of global metabolic and regulatory alterations in response to various environmental stimuli or phenotypic changes after metabolic engineering has been facilitated.
We provide evidence that the latter effect dominates by showing that the premium increases (decreases) in response to enhancement (lowering) of investor protection via regulatory alterations in the rule.
In contrast to cell cycle and developmental categories whose enrichment in both transgenic and tumor gene sets reflects progressive regulatory alterations during carcinogenesis, downregulation of genes associated with protein deubiquitination, a relatively new target for cancer therapy, was first observed in tumor cells.
The PI3K/Akt signaling pathway is strongly associated with regulatory alterations of several prominent metabolic factors.
From these two studies, we can conclude that hundreds to thousands of genes in each genotype contain regulatory alterations.
Motivated by the impact of gene regulatory alterations on carcinogenesis, we studied repeat-associated gene expression changes.
The data presented here reveal a novel regulatory alteration in the quorum sensing module of the microbe.
The regulatory alteration of E-cadherin and Rab11 may vary dynamically in the multistep model of progression of colorectal carcinoma in different stages.
If this microsatellite separates cis-regulatory elements, alterations in its length could affect the binding of transcriptional regulators to these elements and significantly alter gene expression [ 66- 71].
Because small metabolites are intermediates and end products of all regulatory pathways, metabolic alterations represent the most proximal reporters of alterations in our body in response to intrinsic and extrinsic perturbations, and thus may capture the complex physiological or pathological changes that accompany the aging process [ 20].
Previous theoretical study showed how regulatory changes causing alterations in signal strength, could account for the evolution of the sex determination regulatory cascade of D. melanogaster in a step-by-step fashion [ 27].
