Your English writing platform
Discover LudwigExact(4)
However, the pressure reduction between the inlet and outlet of a pressure regulator results in a significant power loss, especially when the pneumatic load requires only a low pressure but a large flowrate.
In this respect, it is interesting to mention that inhibition of Bub1, another mitotic regulator, results in nuclear translocation of apoptin in normal cells.
Our rationale for further analysis was that the modulation (silencing or over-expression) of a transcriptional regulator results in reprogramming of the transcript profile; therefore, we performed transcriptome analysis through a microarray-hybridization approach of transgenic roots from composite bean plants that showed modulated PvTIFY10C gene expression.
The significance of normal ion transport for mucociliary health is shown by the pathophysiology present in cystic fibrosis (CF), wherein dysfunctional chloride transport secondary to a mutation of the gene for the protein CF transmembrane conductance regulator results in abnormal mucus and severe mucociliary dysfunction.
Similar(56)
In Salmonella typhimurium binding of CAMPs to the PhoQ two-component sensor kinase activates the signal transduction cascade from the sensor to the PhoQ response regulator, resulting consequently in the induction of the PhoPQ-regulated promoters [ 24].
Deletion of NLS sequences from four selected nuclear targeting proteins, urease subunit A, Omp18, secreted protein involved in flagellar motility, and response regulator, resulted in cytoplasmic localization of these mutant proteins.
In vitro studies suggest that one underlying mechanism may be the binding of antioxidant components of the herbal medicine to CFTR (cystic fibrosis transmembrane conductance regulator), resulting in direct activation and enhanced chloride transport [11].
Recently, we have shown that allelic replacement of the streptococcal regulator of virulence (Srv), a putative transcriptional regulator, resulted in the constitutive production of SpeB [28], [29].
Induction of this transcriptional regulator resulted in reduced expression of specific ATP-dependent efflux pumps and promoted long-term survival of mycobacteria, while its deletion accelerated bacterial death under nonpermissive growth conditions in vitro and during macrophage or mouse infection.
Such a spectrum of mutations made sense given that loss-of-function mutations in each negative regulator resulted in constitutive activation of the DGC (Goymer et al., 2006; Malone et al., 2007), with ensuing downstream effects (McDonald et al., 2009).
SUMOylation of transcriptional regulators results in alterations to the transcription regulation of individual genes, while the SUMOylation of epigenetic regulators brings about long-range chromatin remodeling, and hence global changes in expression.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com