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This study was performed to investigate whether PGC-1α, a PPARγ coactivator and metabolic master regulator, plays a role in regulating VSMC proliferation and migration induced by high glucose.
An important cell cycle regulator plays a central role in the regulation of cell cycle arrest and cell death is the tumor suppressor, p53 [ 116].
Of course the regulator plays a key role in setting and raising standards; in inspecting homes properly, regularly and when significant changes take place, and in taking measures to tackle poor care, including closing homes if necessary.
Escherichia coli (E. coli) FadR regulator plays dual roles in fatty acid metabolism, which not only represses the fatty acid degradation (fad) system, but also activates the unsaturated fatty acid synthesis pathway.
We demonstrated that the RovA regulator plays critical roles in the construction and functioning of the bacterial membrane, which sheds considerable light on the regulatory functions of RovA in antibiotic resistance and environmental adaptation.
BRDT, one such regulator, plays a critical function in spermatogenesis and acetylation-dependent chromatin remodelling (Gaucher et al, 2012).
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And it insists that the regulator played its "proper role, regulating standards".
GPR119 receptor has been proposed as a metabolic regulator playing a pivotal role in the modulation of glucose homeostasis in type 2 diabetes.
Dietary factors and epigenetic regulator play essential roles in antitumour activities [ 87].
AIRE is a transcriptional regulator playing a functional role in thymocyte education and negative selection by controlling the expression of peripheral antigens in the thymus.
Overall, our data may suggest miRNAs as a dosage regulator playing a possible role in R-genes functional redundancy erosion following large or local duplication events.
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CEO of Professional Science Editing for Scientists @ prosciediting.com