Sentence examples for regulator of death from inspiring English sources

Autophagy has emerged as a key regulator of death pathways.

Autophagy has recently become an important issue in cancer research, and is emerging as a key regulator of death pathways.

A recent report has identified cFLIP (both long and short isoforms) as a crucial negative regulator of death receptor-induced apoptosis in pancreatic carcinoma cells.

EDR2 was isolated as a negative regulator of cell death, specifically the cell death elicited by pathogen attack but not by abiotic stresses.

EDR2 acts as a negative regulator of cell death, specifically the cell death elicited by pathogen attack and mediated by the salicylic acid defense pathway.

To identify novel regulators of death-receptor pathways, we performed a genome-wide siRNA screen in the human glioblastoma cell line U251MG using SMART-pool siRNA library (Dharmacon).

When bZIP10, a positive regulator of cell death [ 59], was knocked out in cat2 bzip10, a reduced amount of cell death was observed [ 18].

In Arabidopsis thaliana, AtMC1 is a positive regulator of cell death and a survival factor for aging plants, whereas AtMC2 negatively regulates cell death.

Mutant huntingtin fragment proteins have now been shown to elevate Bip (an ER chaperone), increase levels of C/EBP homologous protein (CHOP; an ER stress-induced regulator of cell death), increase the phosphorylation of c-Jun-N-terminal kinase (a regulator of cell death) and cleavage of caspase-3 and caspase-12 (mediators of cell death; Reijonen et al. 2008).

The Fas death receptor, which belongs to the tumour necrosis factor receptor family, is a key physiological regulator of cell death especially in immunologically mediated apoptosis (Nagata, 1999).

When K562 cells were transfected and expressing CD95, they were still protected from CD95-mediated cell death [ 74, 75] and it has been suggested that Abl kinase acts as a negative regulator of cell death.