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There were only small additive effects with adrenergic stimulation indicating a possible ceiling effect in up-regulation of Cx43 expression maybe caused by counter regulative mechanisms.
It is of great significance to study the expression patterns and regulative mechanisms of WRKYs in stress responses.
Tsc mutant embryos feature phenotypic variability and developmental delay, though, which may suggest earlier defects that are compensated for by regulative mechanisms.
The broad spectrum of regulative mechanisms originating from very different levels of complexity and acting on very different time scales strongly limits coarse-grained modeling.
These results indicate that K. alvarezii is a low-light-adapted species but possesses regulative mechanisms in response to both excessive and deficient light.
Furthermore, regulative mechanisms become effective in ectotherms, like the induction of specific heat shock proteins helping to adjust the metabolic functioning to seasonal warming [ 3].
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We can speculate that through its binding to Hsp70, BAG3 might also positively or negatively modulate folding of other apoptosis-regulating proteins, and expect that future research will disclose a very complex regulative mechanism mediated by this protein.
Several scholars including Pinker, Chomsky, Edelman, and Luria have indicated the importance of the emergence of human language as an important regulative mechanism of learning and memory in the context of the development of higher-order consciousness (see Neural correlates section above).
However, the pathway and regulative mechanism remain unknown.
These results suggest the possibility of a post-transcriptional regulative mechanism of ADGF-A/AGFP protein expression.
Collectively, these observations demonstrate that the control of precursor maturation and disposal is an early regulative mechanism in the normal insulin production of β-cells.
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