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We present a mathematical model that contains Wnt and BMP, a cell lineage, and their feedback regulations to study formation, regeneration, and stability of multiple crypts.
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For this, we design a synthetic gene circuit with an antagonistic self-regulation to study the spatio-temporal control of protein expression.
All animal studies were designed and conducted under approval from Pharmacyclics Inc. or Bolder BioPath (Boulder, CO, USA) Institutional Animal Care and Use Committee for compliance with regulations prior to study initiation.
Collectively, the present study is aimed to statistically infer the relationship between multiple modulators and modulated gene regulation and to study the associated biological functions in breast cancer.
Flies carrying particular P elements can be crossed to analyze the components of regulation and to study how these components contribute to the repression of harmful transposon activity.
Precise methods for transgene regulation are important to study signaling pathways and cell lineages in biological systems where gene function is often recycled within and across lineages.
Regarding the effect of Itga11 down-regulation, we proceeded to study the neutralization of ITGA11 during differentiation.
Then we will specifically focus on the potential of neurocognitive ERP markers of attention and emotion regulation in order to study the effect of mindfulness training in adolescence.
High mutation frequency and the proteins' key role in transcriptional regulation prompted us to study the genes role in other tumour types.
There is also the ongoing burden of regulation to consider: one study calculated the costs of complying with new banking regulations doubled from 2007 to 2013 to hit $70.2bn for the six largest US banks, thanks to new rules aimed specifically at institutions with assets of more than $50bn.
Controlling protein degradation can be a valuable tool for posttranslational regulation of protein abundance to study complex biological systems.
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