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In the last decade, compelling advances highlighted the pivotal role of EG-VEGF and its receptors in regard to their expressions, multiple roles, and regulations in normal and pathological human pregnancies.
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These observations suggest the CYP3A4 is regulated through tissue specific epigenetic regulation in normal tissue.
Since telomerase activity is primarily regulated through hTERT expression, understanding of hTERT regulation in normal cells is crucial for the understanding of carcinogenesis.
In addition to its role in DNA repair, DDB2 could play an important role in cell cycle regulation in normal cells, when associated with proteins regulating the cell cycle [7], [8].
We identified the miRNAs miR-140 and miR-27a as regulators of these two genes and studied their expression and regulation in normal and OA human chondrocytes.
This study and conclusion are supported by the presence of sensorineural hearing loss in distal renal tubular acidosis, a disorder that is caused by mutations in the pH-regulating H+-ATPase complex, they also support a role for pH regulation in normal hair cell function.
We investigated the mechanism underlying UHRF2-mediated regulation of H3K9ac and H3K14ac expression and the factors associated with differential regulation in normal and cancer cells.
RNA microarray analysis was used to evaluate the impact of 131I and 211At exposure on global transcriptional regulation in normal mouse thyroid tissue.
Therefore, investigating the relationship between RBPs and their RNA targets is critical for a broader understanding of post-transcriptional regulation in normal and disease processes.
Outlining the mechanisms that underlie CTGF gene regulation in normal and fibrotic cells, might help design of future intervention strategies aiming at targeted specific interference with CTGF expression at sites of progressive fibrosis.
OXT is also associated with appetite regulation in normal and in pathological contexts in humans.
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