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The mechanisms underlying this type of regulation warrant further inquiry, as do the other unexpected trends identified in our study, such as the general paucity of known chromatin marks positively identifying closed chromatin and the tendency of large introns to stay in closed configuration even when the genes are expressed.
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Nevertheless the silencing and escape of genes appear to be tightly regulated and the nature of such regulation warrants investigation as it may have therapeutic applications in some disorders such as Rett Syndrome.
The large number of components and interactions involved in dynamic gene regulation warrants a quantitative, computational perspective for investigating the dynamic behavior.
Therefore, the current finding on the mechanistic explanation of the Asteraceae preparations action on ERK regulation warrants further investigation.
The complex functional interplay between the two Hif isoforms has not been fully elucidated in PCC/PGL and, due to the intimate relationship between Hif-2 α and cell-cycle regulation, warrants further investigation in the context of malignant transformation.
Although the molecular intricacies of these regulations warrant further studies, the present study provided evidence that the anti-inflammatory and anti-metastasis activities of embelin may be mediated by its binding to TACE.
Wealth is created by those with the capacity to think outside the box; the global economy meanwhile allows them to move wealth creation across borders when tax and regulation structures warrant it.
These findings identify cases of potentially novel unconventional epigenetic regulation which warrant further mechanistic inquiries.
Justice Alito also suggested that another body might want to adjudicate the dispute between Judge Easterbrook and Judge Posner about whether the recent economic crisis suggested that more regulation was warranted.
Vague claims and oversized promises will backfire as the industry grows, as each overreach makes government regulation more warranted.
As for whether more laws are required to protect net neutrality, the letter argues that "less regulation is warranted" if Internet providers "adhere to a meaningful voluntary code of conduct," while more regulation would be needed if they actually start "impeding specific data flows".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com