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Our findings illuminate the prevalence and dynamic nature of translational regulation underlying the mammalian cell cycle.
Our long term goals are to understand many of the molecular mechanisms and regulation underlying basic cellular processes in bacteria.
McKinney is part of Department Head Alan Grossman's lab, which investigates the molecular mechanisms and regulation underlying basic cellular processes in bacteria.
Recent multi-trait analyses at different phenotypic levels are uncovering the pleiotropy and the genetic regulation underlying high-level complex traits.
Employing genome-wide ribosome profiling, we uncover widespread translational regulation of hundreds of mRNAs serving as an unexpected mechanism for gene regulation underlying cell-cycle progression.
Age-dependent effects identified through novel statistical approaches can provide insight into the biology and temporal regulation underlying BP associations.
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Thus, although we have not measured mechanic tension directly, we can conclude that spectrin regulates Myosin II activity and this regulation underlies the role of spectrin in growth control.
Transcriptional regulation underlies the functional actions of various lymphoid effectors and is the key to further understanding how the immune system works.
These data suggest that epigenetic regulation underlies the differences between the annual and perennial growth forms.
Significantly, the NF-YA-mediated suppression of PLK1 is necessary to prevent adriamycin (ADR -induced mitotic deADR -induceding that this novel mitoticsm for PLK1 regulation undeathes the cell fate determindicatingthatDNA damage.
The promoter analysis identifying transcription factors provides evidence of co-regulation underlying the co-expression or modulation in the pathways.
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