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Although the mechanism regulating PSA expression remains obscure, it might result from post-transcriptional regulation triggered by Schwann cell differentiation.
But Senator Bruno's declaration that he would end regulation triggered a fierce response.
Cells in the control samples for osmotic downshift and blood exposure were diluted at identical ratios in fresh, reduced medium to adjust for differential gene regulation triggered by dilution effects.
The presence of an HS site could be a dynamic feature when it marks regulation triggered by a transcriptional event.
There is a single event of type Regulation (triggered by the verb 'activate'), which has two participants.
Such up-regulation of LH levels is believed to be associated with the reduced negative feedback regulation triggered by decreased testosterone levels in blood circulation.
Similar(48)
However, in the course of progressive heart failure, the continuous expression of CTGF becomes enhanced through autocrine and paracrine regulation triggering an increased activation of prohypertrophic pathways like the Akt kinase pathway.
According to several studies, hsa-miR-200c overexpression inhibits metastasis prostate cancer, while aberrant regulation triggers the invasion and migration of prostate cancer at the post-transcriptional level [ 49].
This may indicate that XDH, with its lower level and strongly NAD+-regulated O2 – generation, normally serves a signaling role that is tightly redox controlled, while under conditions of major oxidant stress conversion to XO removes this regulation, triggering higher levels of radical generation leading to cellular injury and death.
Various chemicals inhibiting PKCs or extracellular signal-regulated kinase (ERK) as well as the knock-down of PKCδ expression counteracted the PMA-mediated increase of pS2 mRNA up-regulation triggered by BZA, demonstrating that it was dependent on PKCs, including PKCδ isoform, and ERKs.
Transfection of a series of reporter gene constructs with or without S/MAR 1 (basepairs –1523 to 10077) and the more distant S/MAR 2 (basepairs –8373 to 68800), into PARP-1+/+ as well as PARP-1-/ cells, revealed an additional, major level of muPARP-1 promoter down-regulation, triggered by PARP-1 binding to S/MAR 1.
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