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These splicing regulators may be involved in MYCN-associated splicing regulation, through which MYCN may exert part of its phenotypic effects on neuroblastoma.
However, the temporal progression and molecular regulation through which Vpr promotes polyploidy have remained unclear.
If these mutations prove to be similarly activating, both NSD members will represent completely novel areas of epigenetic regulation through which small molecule targeted inhibition could be useful.
In their article, Wiener and Bennear offer a detailed analysis of the differences among these instruments, including the choice between "discretionary adaptive regulation," through which an agency or committee might look at new information and make a judgement about how to change the policy, and a system of pre-set automatic adaptive thresholds.
We reason that these divergent lines of evidence could suggest that the ATP-induced allosteric effect of 5-LOX we have characterized herein may be another biologically relevant form of 5-LO Xregulation through which inflammation control can be modulated.
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This is empirically concretised in the context of Finland by analysing freedom of choice in health care as a political technology of re-regulation through which state power is redirected.
The protocols also set the rules and regulations through which all beneficiaries should observe and respect each other's religious and tribal codes of conduct.
Emily Cain, a spokeswoman for OMB, said that as with any rule, OMB's office of information and regulatory affairs conducted an interagency review process "to ensure that the regulations through which agencies implement policies are efficient, well-designed to achieve their objectives, and based upon the best available evidence".
Thus, we identify a novel molecular regulation mechanism through which miR-20b regulates HIF-1α and VEGF and is regulated by HIF-1α so to keep tumor cells adapting to different oxygen concentrations.
It is thought that this might be a novel molecular regulation mechanism through which miR-20b regulates HIF-1 α and VEGF but which is also self-regulated by HIF-1 α so that tumour cells continuously adapt to different oxygen concentrations [ 103].
Considering the drug's prevalence, some states have pursued an approach to regulation called decriminalization, through which the drug remains illegal but enforcement against users is deprioritized.
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