Sentence examples for regulation the expression from inspiring English sources

However, as BRCA1 loss of function is correlated not only to mutations but also to epigenetic changes, such as promoter methylation and microRNA regulation, the expression of miR17, a validated regulator of BRCA1, was measured to confirm this association with respect to BER key enzyme expression.

To specify the fine PRC regulation, the expression levels of the genes and proteins involved in the oxidative phosphorylation process were studied by real time quantitative PCR and western blotting.

Since individual CYP forms differ markedly in their substrate preferences and regulation, the expression profiles of CYP in various cell types are important determinants in tissue-specific toxicity.

To determine the relevance of ETS2-miR-196b ETS2-miR-196b ETS2-miR-196b transcriptionalpregulation Ethe and miR-196b wexpressionigated in two gastric cancer cell lines by RT–qprofiles

Food components play a role in influencing, either directly or indirectly (through hormonal regulation), the expression of genes encoding for proteins involved in energy metabolism, cell differentiation and growth and immune responses.

Interestingly, while both half-sibfamilies G and g exhibited similar proteolysis regulation, the expression of several genes involved in macromolecule biosynthesis, and particularly in protein biosynthesis (cct2, eif4g1, kiaa2018, mrpl22, mrpl27, mrpl30, mrpl34, mrpl48, mrps14, mrps17, rars, rpl18, rplp1 and rps18), were up-regulated in half-sibfamily G.

Correspondingly, with the hTERT down-regulation, the expression level of c-Myc in ZR751 cells was down-regulated after PE extract treatment.

Recently, it is reported that down-regulation the expression of pfkA, a gene encoding phosphofructokinase, increase the HA yield in Bacillus subtilis (Jin et al. 2016).

Moreover, with the deep research of the drug pathway, it (the further mechanism researches) suggested compound 3a could inhibit the apoptosis of injured PC12 cells via blocking the mitochondria apoptosis pathway including up-regulation the ratio of Bcl-2/Bax, down-regulation the expression of cytochrome-c (Cyt-c) and inhibition of the activity of caspase-9 and -3.

However, despite this up-regulation, the expression of Pgp in response to the elevated levels of UCB in jj Gunn rats in the first 2.5 weeks after birth (P2 P17) remained very low compared to adult values (16 and 27% of adult Jj level, respectively).

Noted, the differential expression variance includes tight-regulation (the expression variances of genes in case samples are less than those in control samples) and relax-regulation (the expression variances of genes in case samples are larger than those in control samples).