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In undamaged HeLa cells, both proteins associated with CUL4A and DDB2; and FLAG-BAF also associated with endogenous DDB1 in HEK293∶BAF cells (unpublished observations), implying some kind of ongoing molecular surveillance or regulation that involves the nuclear envelope (emerin) and BAF.
In general, the IFNα/β response has a complex regulation that involves positive and negative feed-back mechanisms, some of which are still unknown.
In this review, we will discuss a novel form of T cell regulation that involves a post-translational modification of proteins by ubiquitination.
Leakage of signal, or crosstalk, from one MAPK pathway to another is prevented by a number of mechanisms, in addition to the negative regulation that involves protein phosphatases (Saito 2010).
Macroautophagy (autophagy) is a pivotal mechanism for catabolic regulation that involves delivering the cytoplasmic cargo sequestered inside double-membrane vesicles to the lysosome and is highly regulated by a limited number of autophagy-related (ATG) genes.
Regarding GADC differentiation in mouse brain under the regulation that involves megane (Guimera et al., 2006), the contribution of the βHLH transcription factor should also be considered in sea urchin embryos.
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Genes related to the PRC2 components were found in grasses and may have roles in gene regulation that involve changes to chromatin structure.
However, this does not take into account mechanisms of translational regulation that involve differential loading of ribosomes onto mRNAs.
The intricate mechanisms of regulation that involve chromatin are largely based on the enormous complexity built into this structure.
Here, we map the TRAIL gene promoter and review studies of TRAIL gene regulation that involve several modalities of gene regulation including transcription factors, epigenetics, single-nucleotide polymorphisms and functionally distinct isoforms.
Somewhat surprisingly given a number of models for developmental regulation that involve higher order inaccessibility of large regions of chromatin [ 37], we observed no genes or regions which were completely inaccessible to DAM modification in vivo.
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