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The difference in the mode of gene regulation reported here for the duplicated fabp1s may be due to loss of cis-regulatory elements in the fabp1a and fabp1b.2 genes, a mechanism consistent with the process of subfunctionalization.
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18This finding holds when using other indices for labour market regulation (not reported here) such as the Fraser Freedom Indices for labour market regulation and the hiring and firing regulation.
Also, the extent to which the differential regulation of genes reported here is applicable to other V. vinifera varieties is yet to be shown, and the investigation of transcriptional changes at more closely spaced developmental stages will provide further valuable information.
The fast regulation of synapse number reported here could thus maintain the level of excitatory activity required for ensuring plasticity-mediated mechanisms.
Given all of these diverse findings, it is reasonable to propose a link between the membrane accumulation of AZT, the induction of phospholipidosis by AZT, the up-regulation of lipid gene metabolism reported here, and the final clinical outcome.
It would be of interest to determine how COUP-TF tregulationonal regulatisn is achieved, and whether it involves Wnt signalling, another regulator of COUP-TF expression reported here.
The regulation of the sequenced biomarkers in the 'DN model', as reported here, shows a consistent pattern that is apparently specific for DN.
In summary, the results reported here are the first to describe the regulation of HKIII expression and activity and to characterize the role of HKIII in cytoprotection.
The data reported here provide important new insights into longevity regulation.
The data reported here suggest the following model for the regulation of the activity of TAp63α in oocytes.
In the studies reported here, we focused on the biological implications and regulation of one disease-related target, dfmr1, by the siRNA pathway component Ago2.
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