Sentence examples for regulation of origin from inspiring English sources

One potential role for a temporal regulation of origin firing is to minimize fluctuations in replication end time and avoid persistence of unreplicated DNA in mitosis.

However, it gives some indications on the temporal regulation of origin firing.

Finally, origin-specific trans-acting regulators of origin activity could be cell-type specific, allowing an additional level of regulation of origin activation.

Our data highlight the importance of chromatin features, such as the NDR and nucleosomes +1 and -1, in the regulation of origin activation and timing.

These findings elucidate the mechanism of action of Rif1 in the control of DNA replication and demonstrate a role of PP1 phosphatases in the regulation of origin firing.

While ACS, B1 and B2 elements participate in recruitment of factors needed for pre-replicative complex (pre-RC) formation, the B3 and B4 boxes are involved in regulation of origin efficiency [ 1, 2, 3, 4, 5, 6, 7].

It is granted that histone acetylation can play a key role in the regulation of origins of DNA replication [2], [3].

We considered that an event in Mitosis or G1 that is important for regulation of origins could be impaired in Δgcn5 cells.

To elucidate the role of the chromatin environment in the regulation of replication origin activation, autonomously replicating sequences were inserted into identical locations in the budding yeast genome and their activation times in S phase determined.

Bacteriophage T4 UvsW protein is involved in phage recombination, repair and the regulation of replication origins.

Despite conservation of the proteins that comprise the preRC in all eukaryotes, very little is known about the sequence elements required for the selection and regulation of metazoan origins.