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Group I mGluRs play an important role in the regulation of network activity in the hippocampus [20] [22].
In this work, we shall try to bridge two rather unconnected approaches in analysing regulation of network properties.
This suggests that altered synaptic transmission and altered spiking activity may have distinct effects on homeostatic regulation of network excitability.
It was reported that in plant development process, the up- or down-regulation of miRNAs might play a more important role in the regulation of network [ 39- 41].
Thus, the causal relationship between these 2 trans-synaptic inhibitory mechanisms not only extends our knowledge on the physiological regulation of network excitability, but can also open the path to new therapeutic strategies.
They showed that age-related changes preferentially affect only a few modules (communities, groups) of the network, and aging-associated proteins are typically located between modules, providing an important element of the regulation of network functions.
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This suggests that the de-regulated miRNAs are involved in co-ordinate regulation of networks of functionally related genes.
That's why organizations like the National Alliance on Mental Illness have called upon officials to find ways of further improving mental health coverage -- whether by providing people with more protection from high deductibles or strengthening the regulation of networks of mental health care providers.
Specifically, since a network connecting two cancer genes represents cross-connections between signaling pathways, one would expect that perturbations along a pathway would result in altered regulation of network-associated nodes.
Furthermore, DOC levels appear to be responsible for the regulation of networks of genes involved in the neuronal processes that underlie many aspects of brain function and likely the correlated ethanol phenotypes.
Despite this limitation the computational analysis of microarray data reveal novel insight into the regulation of networks of TFs acting in concert.
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