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System design, regulation of level of automation, managing distraction, and selection of fatigue-resilient personnel are all possible interventions for passive fatigue, but careful evaluation of interventions is necessary prior to deployment.
Specifically, evidence from human neuroimaging has shown that the same brain structures are implicated in both emotional processing and the regulation of level of consciousness [1], [2].
Given the adaptive regulation of level of goal/action identification typically seen in healthy controls, it is a plausible hypothesis that psychological disorders may involve impaired regulation of level of goal/action identification.
Furthermore, there is evidence that this regulation of level of goal/action identification is abnormal in a number of psychological disorders, indicating that this process is a possible transdiagnostic process.
Thus, if level of goal/action identification causally influences self-regulation and impulsivity, (dys)regulation of level of goal/action identification may be a factor relevant to the onset and/or maintenance of these disorders.
Thus, mild depressive symptoms are associated with the adaptive regulation of level of goal/action identification in response to mood, but more extreme depressive symptoms are associated with dysregulation of this process.
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The regulation of levels and composition of glycosylation might impact the subcellular location and stability of EpCAM.
Decreased expression of PKc in potato tubers shows the importance of PKc in regulation of levels of pyruvate and related oxidase in heterotrophic plant tissue [ 41].
Analyses of PHAII pathogenesis suggest that the regulation of levels of WNK kinase protein is an important regulatory mechanism of WNK OSR1/SPAK SLC12 signaling.
Thus, the regulation of levels of reduced thioredoxin and the (SH 2Trx-ASK1 complex may be part of the mechanism of resistance to oxidative stress in long-lived mice [ 50].
It had not been clear how this fit with the observed E2 regulation of levels of TSPO ligand binding and TSPO mRNA (39 – 42).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com