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Cellular pH regulation has previously been shown to regulate cell death processes, although this regulation is complex (Matsuyama and Reed, 2000).
These results suggest that PRNP gene expression can be regulated by both ATF6α and XBP1, but that the regulation is complex and depends on the cellular context.
Flowering regulation is complex, with the release of FT controlled by more than 30 proteins in interacting cascades.
Human body-weight regulation is complex and is rooted in a superstructure that takes in sensory signals from food, neuro-hormonal signals from the digestive tract and signals from the body's energy reserves.
As mentioned before, mycotoxin regulation is complex and many factors are influencing their formation, including nutritional factors.
In higher eukaryotes, transcriptional regulation is complex.
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45, 46 There have currently been over 300 regulator proteins identified, and their interactions within ER transcriptional regulation are complex.
56 IGF-1 variants mediate growth hormone signaling, and IGF-1 functions and regulation are complex and tissue specific.
The cellular outcomes of miRNA-mediated gene regulation are complex, as some miRNAs decrease while others increase cell growth, and still others increase the level of apoptosis [ 22].
The landscape for both federal and state regulations is complex and dynamic.
The process of developing appropriate regulations is complex, however, and depends on many considerations beyond those established to a high degree of scientific certainty.
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