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At the time of writing, HTRIdb housed a collection of 51871 unique experimentally verified transcriptional regulation interactions among 284 TFs and 18302 TGs detected by 14 distinct techniques (these data are accessible via the "Statistics" button in the HTRIdb main page).
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Thus, the requirement for a given transcriptional complex to regulate a promoter might depend on the severity of osmostress and be determined through the regulation of interactions among transcriptional complexes (Zapater et al. 2007).
As molecules in the immune response category are always communicating with each other, we performed a network-based analysis to identify aberrant regulations or interactions among differentially expressed molecules observed in this study.
In goldfish, sexually active males release, via the gills, relatively large amounts of androstenedione [ 6] which stimulates pushing behaviour (a component of male-male competition) [ 31] and has been suggested to act as a male pheromone (as part of a blend of steroids dominated by androgens) in the regulation of competitive interactions among males [ 2, 6, 31].
Gene regulation is underpinned by interactions among regulators, including transcription factors and miRNAs and their target genes.
We define three sets of hidden variables, These variables govern the state of genes, regulations of genes and interactions among genes respectively.
In the past decade, there has been a rapid development in systems biology approaches driven by high-throughput data characterizing regulations of genetic networks, interactions among proteins, and reactions in metabolic pathways.
The instructor promoted extensive independent learning, learning regulation, continuous dialogue and collaborative interactions among peers.
Gene regulation is exerted by cooperative interactions among TFs that binds to clusters of sites within cis-regulatory regions.
Previous studies have reported a complex regulation system that includes epistatic interactions among genes and QTLs for heading date of rice [ 2, 5, 8].
Our analyses found a general conservation of regulation genes and of their interactions among the different considered species, and may serve as a guide to extrapolate regulatory data from model species to lesser-known environmentally (or medically) relevant species.
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