Sentence examples for regulation indicative from inspiring English sources

Equally as important, our results indicate bimodal genes capture epigenetic aspects of gene regulation, indicative of gene expression levels that are stable across cell divisions.

An N-terminal basic domain of Dia is critical for this regulation, indicative of an electrostatic-based direct interaction between Dia and PI 4,5 P2.

Specifically, a novel "CT" deletion found in 7 of the 14 globally diverse populations altered the predicted mRNA targets of hsa-mir-4640 to include 3 additional targets and removed all of its 79 original predicted targets from regulation, indicative of the disruptive potential of seed sequencing indels on miRNA function.

All three retinoids were also able to regulate to a similar extent both genes in purified primary Schwann cell cultures (Fig. 7B), although TTNPB was more potent, specially regarding RAR-β up-regulation, indicative of its higher affinity for RAR binding compared to the natural retinoids [32].

Therefore, high variability of a gene's expression may point to the complexity of regulation that is indicative of its signal or adaptive role.

Whether these differences are important for regulation or are indicative of co-adaptation with alterations in the γ-TuSC binding sites remains to be seen.

P450 genes are known to be important in detoxification [45], and their down-regulation may be indicative of exhaustion (although we did not observe an early up-regulation of these genes).

Alternatively, their down-regulation may be indicative of Bd-derived toxins, as perturbation of liver P450 function can be endotoxin-mediated in other systems [46].

Restricted inflammatory responses in SL damaged skin were in parallel with massive up-regulation of chaperones indicative of the induction of UPR.

Analysis of syntenic regions of the mouse genome shows that few noncoding exons are shared between human and mouse, yet human splicing profiles are recapitulated on Hsa21 in mouse cells, indicative of regulation by a deeply conserved splicing code.

The decreased negative regulation of TRX was indicative of lower antioxidant activity and increased oxidative stress.