Sentence examples for regulation in subtypes of from inspiring English sources

We believe that alternative pathways can at least partially overcome ER regulation in subtypes of breast cancer.

Our findings provide the rationale for the incorporation of dual PI3K/mTOR inhibitors in treatment strategies aimed at patients with t(4 14) or t(14 16), and set the scene for future mechanistic studies on cell cycle regulation in these distinct subtypes of MM.

Moreover, the same set of effector genes can be regulated by different combinations of transcription factors, as shown recently for regulation of dopamine pathway genes in different subtypes of dopaminergic neurons in C. elegans (Doitsidou et al., 2013).

"We've been able to reduce the overuse of chemotherapy in about one-third of all patients in some subtypes of breast cancers," Daniel Hayes said.

To elucidate the role of miRNA regulation in this specific cancer subtype, we applied our algorithm to the Maire dataset including only TNBC samples (n = 37).

Previous studies have revealed complex genetic aberrations affecting almost all chromosomes with up- and down-regulation of several genes in this subtype of CTCL.

Clontech Microarray (overexpression in 64% lung cancer samples) and RT-qPCR (down-regulation in 38% of ADC and in 81% of SCC samples) were not in concord because different cancer subtypes were present in studied microarray samplings.

Investigations of those specific neuronal populations suggested roles for Runx1 in the regulation of neuronal subtype specification and axonal targeting [8] [13].

Elucidating the regulation of mammary cell differentiation hierarchy may lead to the identification of novel factors in the regulation of initiation and progression of various subtypes of breast cancer.

There are more than ten subtypes of CyPs in mammals, distributed in different subcellular compartments, that function in numerous cellular processes, including transcriptional regulation, immune response, protein secretion, and mitochondrial function [7] [9].

There are different histological subtypes of neoplasm in adults.