Sentence examples for regulation in conditions of from inspiring English sources

Thus, tubulin acetylation may be a prerequisite for transport of cargo to the aggresome but RanBPM does not appear to be involved in this regulation in conditions of proteasome impairment.

Although we can not completely rule out some degree of transcriptional regulation of ACC in conditions of reduced SCD1, especially in the stable SCD1-knockdown cells, its long half-life (∼3 days) [48] suggests that a different regulatory mechanism is operating under SCD1 inhibition.

However, the regulation of its metabolism in conditions of intermediate oxygen availability is not well characterised.

Finally, we identify a role for both Rac1 and Cdc42 in the regulation of VEGF protein expression in conditions of hypoxia.

Functions of P2X2 and P2X7 receptor subtypes in conditions of down-regulation of receptor gene expression were studied by stable RNA interference.

Further, the down-regulation of oxidative stress in S. cerevisiae in conditions of 2.8% oxygenation compared to fully aerobic conditions was found to be related and potentially restricted to the down-regulation of peroxisomal activities.

The function of sST2 as a biomarker of mechanical stress was first demonstrated in vitro after up-regulation of its gene transcript was noted in conditions of myocardial strain [ 21] and has further evolved with the identification of its ligand, IL-33, which is also induced by myocardial strain.

The up-regulation of Sod2 may contribute to neuronal survival in conditions of increased ROS production.

These observations suggest that after induction of DNA damage, in addition to stabilizing p53, USP7 can also stimulate p53 DNA-binding and serve a dual role in p53 regulation under conditions of cellular stress.

Moreover, PGC-1 α has been implicated in the regulation of skeletal muscle mass, particularly in condition of muscle atrophy.

While there is an infinite number of conditions and their combinations, certain conditions can be viewed as essential and our understanding of transcriptional regulation in such conditions is critical for associating macroscopic phenotypes with regulatory pathways.