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Taken together, our analyses clearly demonstrated that ceRNA regulation highly depends on states of the essential factors and thus may involve complex and dynamic processes in vivo.
Our results suggest that gene distribution in the genome has evolved to allow suitable regulation: highly expressed genes tend to be shorter, and have extensive promoters and terminators.
As expected, the combinatorial arrangement of transcriptional regulation highly increases the overall possibilities to fine-tune the cellular response under different conditions.
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They set a limit to restrictive government interference in markets through heavy regulations, highly distortionate taxation or slow response to demand for goods and services produced by the public sector.
The gene expression study by Bachmeier and colleagues revealed that MMP-3 up-regulation highly depended on histological evidence of disc degeneration [ 19].
Rather than worrying if a school is public or private, it is better to think of all schools along a continuum of regulation, from highly regulated to relatively unregulated.
The World Health Organization (WHO) estimates that at least 30% of countries in the world have either no drug regulation or highly poor capacity to regulate.
Jason Chalik, a lawyer who has represented clients injured and killed in parasailing accidents, said any regulation was highly unlikely, mostly because Florida's Legislature dislikes regulation in general.
The REACH Regulation is highly complex, and its requirements need to be implemented step by step.
We propose that the fragile nucleosome promoter architecture is adapted for regulation of highly expressed, growth-related genes.
NΔ11 and NΔ15 enzymes were insensitive to allosteric regulation and highly active in the absence of the activator.
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