Exact(2)
So far, most works about the aES regulation highlight putative mechanisms operating in Sertoli cells, relegating spermatids to a role of merely spectators.
The literature on motivation and emotion suggests two strategies to promote emotion regulation: highlight controllability of actions and promote reappraisal of failure.
Similar(57)
The Biological Process category was found to be considerably over-represented in the annotations of Hdac1-regulated genes, within which the sub-categories of GO terms related to Transcriptional Regulation (highlighted in purple, Additional file 2) or Developmental Processes occurred particularly frequently.
Our integrated approach to studying gene regulation highlighted two miRNAs that target genes in key biological processes associated with cell survival/apoptosis, ECM-cytoskeleton signaling, and HSPG binding.
Screening of loci, involved in renal water salt balance regulation, highlighted the mineralocorticoid receptor gene NR3C2 as a potential target for several miRNAs.
The preponderance of enhancers around developmentally important genes, as well as their notable role in gene expression regulation, highlights them as a key component of vertebrate developmental regulatory networks.
However, the complexity of this single avenue of gene regulation highlights the need for intense study, especially given the fact that a vast array of additional mechanisms exist that manage the expression and function of MeCP2 at every level.
I will briefly review the current state of knowledge of circadian system and mood regulation, highlighting network properties and system dynamics as key mediators of neural plasticity, which underlies the circadian rhythm-mood connection.
The widespread use of alternative (folk) medicine practitioners in some fSU countries and the growth of this form of health care provision in the post-Soviet period in conditions of variable licensing and regulation, highlights the urgent need for more research on this phenomenon and its potential effects on population health in the countries in this region.
In contrast to the number of in silico annotated putative TAP very few of them have been analysed at the molecular level, essentially histones and proteins involved in epigenetic regulation, highlighting that molecular validation of the factors has to be expanded.
The picture is complicated by heterogeneity caused by differences in cellular origin or stochastic clonal evolution 12. Furthermore, recent studies seeking to understand the role of DNA methylation in normal cells have uncovered previously unappreciated functions of the DNA methylome in gene regulation, highlighting the diverse ways that this epigenetic mark is utilized in mammalian genomes 1.
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Justyna Jupowicz-Kozak
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