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"Relax" may be too strong a word, though, because although one regulation has changed, another has been added.
This finding suggests that gene regulation has changed considerably in response to local environmental conditions.
This result suggests that TU rearrangements have caused the regulatory shift of a number of those genes whose regulation has changed with respect to their E. coli orthologs (from 23 to 54% depending on the organism).
While individual snoRNA genes are found in all eukaryotic genomes, snoRNA gene organization and regulation has changed considerably throughout evolution, favoring the colonization of introns to exploit host gene promoters to transcribe multiple snoRNAs from a single promoter (45).
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Patterns of vertebrate gene regulation have changed during the course of evolution.
The British Bankers Associationn (BBA) said: "Since the onset of the global financial crisis, banks and banking regulation have changed completely.
Be aware that the country's road regulations have changed.
Since our policies were revised five years ago, laws have changed, regulations have changed, and times have changed.
"The training has changed, the technology has changed, the regulations have changed," Mr. Oswald said last week.
One problem, critics say, is that the circumstances surrounding fire safety regulations have changed.
Allison believes it is Newey's innovation and conceptual vision in an era where regulations have changed that has ensured his success.
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