Sentence examples for regulation associated to from inspiring English sources
The objective of the present study was to investigate whether proteinuria can be reversed and to identify the structural modifications and the gene/protein regulation associated to this reversal.
Hence, these findings demonstrate that VvZIP3 gene encodes a putative Zn transporter that may participate in the uptake of this element in Vitis vinifera L.. The tissue-specific expression determined for grapevine ZIP encoding genes reflects the complexity of this gene family and suggests a differential gene regulation associated to the nutritional requirements of grapevine.
On the other hand, however, the more stringent epigenetic phenomena, and those that are triggering more widespread fascination, are those that typically resist change, those states that defy in their stability the inherent disruption of genome regulation associated to the cycles of reproduction in cells or organisms.
Moreover, the present results on PTGDS may be useful to provide a common target for advanced study, aimed to analyze pain mechanisms and pathways at the molecular level, particularly in the case of CA. The increase of urinary PTGDS observed also in patients taking triptans could be an early indicator of a nervous system driven up-regulation associated to chronic pain, as in the case of MOH.
Consistently, miR-101 over-expressing RD18 cells showed 50%% EZH2 down-regulation associated to cell cycle slow-down (5.4 ± 0.6 % increase of cells in the G1 phase and 14 ± 2 and 3.4 ± 0.6 % decrease in S and G2 phases, respectively) and a more modest but significant reduction of colony formation of about 20 and 15 % on either in culture dishes or soft agar (Additional file 4: Figure S4).
Both regulations were associated to relevant biological functions, the former playing a role in cancer proliferation [ 28], while the latter in vertebrate brain physiology [ 26].
Rac1 up regulation has been associated to RhoA inhibition and linked to the modulation of the cytoskeleton [ 65].
DNA methylation is one of the major epigenetic mechanisms that regulates gene transcription and it was shown to be involved in the regulation of genes associated to lipid metabolism, such as fatty acid desaturase 2 (FADS2) [ 17] or peroxisomal proliferator-activated receptor alpha (PPARα) [ 18].
These signaling pathways are crucial to maintain intestinal epithelium homeostasis by balancing the rate of proliferation, apoptosis, and differentiation along the crypt-villus axis, and their de-regulation is commonly associated to colorectal cancer initiation and progression [ 23].
When looking at the S. dulcamara genes common only to either or both of the other two Solanum species (i.e. not to Arabidopsis and rice), molecular functions associated to regulation of gene expression and regulation of protein activity were enriched (Table 4).
The observed clustering of differentially expressed genes could not be attributed to (p ppGpp or DksA regulation associated with the -10 to TTS region of these genes.
