Exact(5)
β-Catenin is involved in a number of cell processes, including the structure of cell membrane complexes, transcriptional regulation, altering cell proliferation and regulating apoptosis (Heasman et al, 1994; Sanson et al, 1996; Gumbiner, 2000; Jamora and Fuchs, 2002; Ferenc et al, 2009).
Allosteric interactions with metabolites upstream or downstream in an enzyme's metabolic pathway cause feedback regulation, altering the activity of the enzyme according to the flux through the rest of the pathway.
Genotypic variations at SNP positions bring new possible binding sites, which may introduce novel modes of gene regulation, altering gene expression and thereby impacting disease progression.
Direct regulation, altering the informational environment, and altering the built environment are the least costly, most logistically feasible, and most effective noise reduction interventions.
The presence of SNPs either in the genomic miRNA sequences or in the 3′UTR of cancer-related genes could influence miRNA-dependent regulation altering consequently tumor susceptibility [ 10].
Similar(55)
The dominant effect of the Rap1– Rifusionusinn in diploid cells and its ability to shorten telomeres in haploids may be due to altered cell cycle regulation, altered affinity, loss of end protection, or a combination of these factors.
Such decrease in mRNA level might be due to transcriptional control (altered synthesis) and/or post-transcriptional regulation (altered stability) of disrupted cellular transcripts.
Other pathogenic mechanisms of TRPC6 mutation that have been hypothesized include altered channel regulation, altered interaction with other slit diaphragm proteins, and altered protein turnover [ 3].
Metabolomics allows for a global assessment of a cellular state within the context of the immediate environment, taking into account gene expression, genetic regulation, altered kinetic activity and regulation of enzymes, and changes in metabolic reactions [ 7– 9].
One of the mechanisms contributing to the TrkB regulation altered the physiological ratio of mRNAs encoding for TrkB isoforms and favored the expression of TrkB-T1 over TrkB-FL.
Nowhere in the world, says the labour minister, Norihisa Tamura, are "core" labour regulations altered only in certain places.
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