Sentence examples for regulation alterations from inspiring English sources

Given the role of mitochondria in oxygen consumption, metabolism and cell death regulation, alterations in mitochondrial function or dysregulation of cell death pathways contribute to the genesis and progression of cancer.

However, it is not clear from the present point of view if the hyperoxic protein regulation alterations are limited to the first few days after exposure or if the proteomic technique used in this study failed to identify further regulated proteins at day 7. Rostami and colleagues [ 13] also published some evidence for an only short-lasting protein effect of hyperoxia exposure.

The methylation analysis in these two genes did not show a difference in tumors compared with normal tissues, indicating the loss of the gene expression was not the result of DNA hypermethylation but most likely due to other transcriptional regulation alterations in tumor cells.

Abnormal autonomic function is been described in all aspects of regulation including alterations to afferent nerve activity, central processing, ganglionic and efferent innervation and alterations to the heart itself.

Although the mechanisms responsible for the down-regulation of SVCT2 expression in osteoarthritic tissue were not explored in the present study, this down-regulation suggests alterations in the transcriptional regulation of SVCT2 by one or more of various factors.

As shown in Fig 4A, the pathways altered in polypoid lesions were predominantly concerned with cell-cycle regulation, whereas alterations in oxidative phosphorylation, ubiquinone metabolism, and IGF-1 signalling were more characteristic of the nonpolypoid transformation process.

The game actors in "10 Items" — John Lehr, Roberta Valderrama, Jennifer Elise Cox and others — seem to have dodged their profession's regulation surgical alterations and starvation diets.

Since the rapid desensitization of 5-HT3A receptors during sustained activation [45], [46], [47], [48] has great importance for synaptic regulation [16], alterations of the tertiary and quaternary structure may also have implications in the pathophysiology of schizophrenia.

One form of such regulation involves alterations of the secondary structure of messenger RNA (mRNA).

Dysfunctional FAP regulation by alterations of these regulatory conditions may severely deteriorate muscle health, affecting both muscle function and metabolism.

Basal autophagy requires tight regulation as alterations in autophagy have been associated with many pathological conditions, including cancer.