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These studies clearly indicate a role for nutrition in regulating transporter mRNA and possibly also protein levels.
Therefore we evaluated the role of this transcription factor in regulating transporter and phase I/II metabolism genes in small intestine during fasting.
S. cerevisiae responds by up regulating transporter proteins, such as Pma1 and Pdr12, which secrete protons and carboxylate anions, respectively, to avoid toxic accumulations.
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Recent studies have suggested the involvement of two IdeR (Iron dependent Regulator) regulated transporter proteins Rv1348 and Rv1349, also known as IrtA and IrtB respectively, in carboxymycobactin mediated iron acquisition and survival of mycobacteria in mouse infection model [10], [11], [12].
The activity of membrane-based pHi regulating transporters was studied in EMT-6 and MGH U1 cells grown in monolayer culture, spheroids, and tumours.
Zinc regulated transporter.
Iron regulated transporter.
We design an expression regulation system utilizing a native Escherichia coli stress promoter, PgntK, to provide negative feedback to regulate transporter expression levels.
According to the Rice Annotation Project Database (RAP-DB, http://rapdb.dna.affrc.go.jp/index.html), one Fe regulated transporter gene, OsIRT1 (Os03g0667500) is localized within the q FETOX-3 region.
As introduced above, CNT1 is a highly regulated transporter protein.
In fact, mptABC was hypothesised to represent the iron regulated transporter IrtAB in MAP [ 40].
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