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But I do not see this as a matter of regulating expression OR regulating transport – I think that the pre-miR structural features are involved in both processes in a unified way.
Analysis and annotation of the predicted target genes showed that they were with diverse functions, ranging from genes encoding transcription factors involved in transcription regulation to genes encoding enzymes involved in metabolism, genes regulating transport, genes encoding various kinases, genes regulating oxidative reduction and genes encoding isomarase and helicase (Additional file 6).
Because the interactions between FG domains may be modulated by certain forms of transport factors, our results indicate that transitions between brush morphologies could play an important role in regulating transport across the NPC, suggesting novel forms of gated transport across membrane pores with wide biomimetic applicability.
The sustained loading may compromise tissue viability either directly, by geometrically distorting cells, or indirectly, by distorting the vasculature or lymphatic networks or, at the micro-scale, by distorting cellular organelles involved in regulating transport, e.g. the plasma membrane, since transport-control-mechanisms are essential for adequate biological function of cells.
This effect may be mediated by differences in secondary structure between isoforms, preferential binding to each isoform by factors regulating transport or translation, or by isoform differences in polyadenylation.
In contrast to a simple static tethering model of BicD function, or a role only in initial dynein recruitment to the cargo, our data uncovers a new dynamic role for BicD in actively regulating transport.
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We have other costs that are rising – regulated transport and distribution costs, environmental costs, metering costs.
He could do far more to open up a statewide market for water, regulate transport fees and encourage experimentation with the aquifers.
Time trends also indicate knowledge diffusion that could improve Russia's ability to regulate transport safety.
Especially in the second half of the twentieth century, many economists argued in favor of liberalizing the heavily regulated transport sector (for Germany see [29]).
Fine-grained particles act as an efficient scavenger and hence regulate transport and sediment accumulation of heavy metals in rivers and streams (Zonta et al. 1994; Sharmin et al. 2010; Mohiuddin et al. 2010).
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