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The inhibition of mevalonate synthesis and the depletion of one or more mevalonate metabolites is the mechanism regulating this phenomenon.
This could mean that either the VDR is being recruited to other regions of the genome and controlling the transcription of TCF7L2 directly, or the VDR is regulating this phenomenon through a 1,25(OH 2D3-sensitive intermediary.
However, Notch receptors regulating this phenomenon are unknown.
It was noted that these features mirrored those of a CD4+ Th2 response and therefore a potential role for T cells in regulating this phenomenon.
This review summarises current knowledge on hyponasty with a particular focus on the role of ethylene in regulating this phenomenon and its possible adaptive significance.
This review focuses on the current available evidence supporting the concept of angiogenesis in human pre-malignant lesions and the putative mechanisms regulating this phenomenon.
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Which loci are of importance to regulate this phenomenon will be an exciting source of inquiry in upcoming years.
The mechanisms that regulate this phenomenon have only been clarified during the last two decades.
However, at the intermediate time points (24 to 72 hours), few genes were regulated; this phenomenon was called a "dip" by van de Mortel et al. (2007).
Low level methylation of some CpG islands is also seen in the normal colonic mucosa and increases with age; however, it is still unclear what other factors regulate this phenomenon.
This indicated that mRNA was not the only molecule in the cell capable of regulating transcription; this phenomenon became known as transcriptional attenuation.
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