Sentence examples for regulating this gene from inspiring English sources

Molecular mechanisms responsible for ESR1-mediated regulation of its downstream target genes (i.e., FOXA1, GATA3, CCND1 and TFF1) in normal and/or pathological conditions have been well characterized (Carroll et al, 2005; Eeckhoute et al, 2007; Krum et al, 2008), however, upstream regulators of ESR1 and molecular mechanisms for regulating this gene are poorly understood (Hosey et al, 2007).

This fact suggests a high conservation of the system regulating this gene in mammals.

However, mRNA levels were similar in the two lines before infection contrary to the difference in H3K4me3 levels suggesting that additional factors are responsible for regulating this gene.

Theoretically, if the inhibition of a certain gene can affect the pathogenesis and development of a disease, drugs regulating this gene might be effective for its treatment.

For the COX VIII subunit, negative effects of Id-1 were also demonstrated, strengthening the idea that bHLH proteins are important in regulating this gene.

Overall, these findings indicate that even when two plants have similar genes (orthologues) in their genome and even if these genes show similarities in their transcriptomic responses, it is possible that the factors regulating this gene expression can differ.

Processes involving DNA methylation and chromatin modification as well as post transcriptional, post translational and epigenetic control mechanisms, forming multiple tiers of regulation, regulate this gene expression.

We speculate that NPAS2-ARNTL/BmalI may regulate this gene as either an enhancer or a silencer and the implant placement may disproportionately activate its anabolic function.

Moreover, L. mexicana [ 17] and L. donovani [ 33] mature intracellular amastigotes also down-regulate this gene.

Theoretically, a given gene's expression pattern can become increasingly complex with the increasing number of transcription factors that regulate this gene, either directly or indirectly.

It is, therefore, likely that these elements could be components of a novel mechanism common to all vertebrates that regulates this gene complex.