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However, it is unknown whether TLX itself is involved in regulating the inflammatory response in the hippocampus.
The ability of regulating the inflammatory response of nanocrystals through peptide surface coating may be of great value for in vivo applications of LNs and other engineered nanomaterials.
Thus, the DC/NK cell cross talk can be identified as a critical node of cellular network regulating the inflammatory response in tissues, and triggering the adaptive response in secondary lymphoid organs [20], [21].
Their potential role in regulating the inflammatory response to LPS warrants further investigation.
ET-1 activates adhesion molecule expression, which may be important in regulating the inflammatory response.
TNF-α is a cytokine with a variety of endogenous biological activity, regulating the inflammatory response and immune response.
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Our data suggest that the level of C/EBPβ-3 in brain plays an important role in regulation, although there are likely additional pathways that are involved in regulating the inflammatory responses.
Animal studies showed controversial effects of hypothermia on NF-κB, a transcription factor that plays a central role in regulating the inflammatory responses [34]-[37] [34]-[37]
The details of the functions of these molecules remain unclear; however, a few studies have indicated that these molecules are involved either in regulating the inflammatory responses or in maintaining the protumoral functions of macrophages.
Although we do not detect IL1 expression, we nonetheless find extensive regulation of other genes that regulate the inflammatory response.
To determine whether integrin α3β1 regulates the inflammatory response to B. burgdorferi by regulating association with the macrophages and subsequent endocytosis, U937 macrophages were stably transduced with shRNA targeting integrin α3 or control prior to stimulation with the spirochetes.
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